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Effect of balancing positive end-expiratory pressure with intra-abdominal pressures on cardiorespiratory function during laparoscopic surgery with trendelenburg positioning

Effect of balancing positive end-expiratory pressure on cardiorespiratory function in patients with trendelenburg positioning during laparoscopic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008861
Enrollment
Unknown
Registered
2016-07-19
Start date
2016-08-01
Completion date
Unknown
Last updated
2017-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung damage

Interventions

experimental group-1:PEEP=12-14cmH2O
control group:PEEP=8cmH2O

Sponsors

Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ASA I-III status patients scheduled for coloractal and pelvic laparoscopic surgery, patients >18 yr of age.

Exclusion criteria

Exclusion criteria: 1. Major cardiovascular, pulmonary, renal, and hematological disorders; 2. obstructive pulmonary disease, repeated systemic corticosteroid therapy for acute exacerbations of chronic; 3. obstructive pulmonary disease, asthma, and previous thoracic surgery or neurosurgery. body mass index; 4. (BMI) N 30 kg/m2.

Design outcomes

Primary

MeasureTime frame
oxygenation index;pulmonary shunt;A-aDO2;driving pressure;CO;SV;SVV;CI;—

Secondary

MeasureTime frame
HR;BP;SpO2;PIP;BMI;BIS;CVP;—

Countries

China

Contacts

Public ContactXueyin Zhang

Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.

shixueyin1128@163.com+86 021-25078999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026