Chronic Obstructive Pulmonary Disease
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients meeting the GOLD2015 diagnostic criteria for COPD.(a ratio of postbronchodilator forced expiratory volume in1 second [FEV1] to forced vital capacity of <70%,and a postbronchodilator FEV1 of <80% of the predicted value) 2. Patients aged 40 years and more; 3. Patients were past or present cigarette smokers with at least a 10 pack-year smoking history; 4. Patients were studied when clinically stable for at least 4 weeks following an exacerbation; no change in any therapy; no received systemic glucocorticoids.
Exclusion criteria
Exclusion criteria: 1. Combined with asthma, tuberculosis, lung cancer, Bronchiectasis and other severe respiratory diseases; 2. Combined with heart failure, long QT syndrome and arrhythmia; 3. Combined with severe digestive system diseases such as ulcer, hepatitis; 4. Combined with other serious diseases such as: nerve, endocrine, blood system diseases and kidney disease, rheumatism and malignant tumor; 5. Allergy to erythromycin or other severe adverse reactions, and patients can not cooperate with the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exacerbations of COPD; | — |
Secondary
| Measure | Time frame |
|---|---|
| ling function; | — |
Countries
China