migraine
Conditions
Interventions
High- dose group :13.5g oral-surcose per day
Medium- dose group:9g oral-surcose per day
Low- dose group:4.5g oral-surcose per day
Sponsors
School of Public Health,Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male or female non-premonitory migraine patients between 18-65 years old. 2. Diagnosed as migraine according to the diagnostic criteria specified by the International Classification of Headache Disorder, 3rd edition (beta version) and initial of age is less than 50 years old; 3. Migraine present for at least three years and patients having 2-6 attacks per month; 4. Moderate ti severe pain (VAS=3.6)which affected the work and learning; 5. No prophylactic drugs of migraine such as beta-blockerscalcium channel blockersantiepileptic drugs and son on were taken in the past 3 months.
Exclusion criteria
Exclusion criteria: 1. Having analgesics more than 10 times due to the migraine attacks every month; 2. Special types of migraine such as ophthalmoplegia hemiplegic migraine type; 3. Cluster headache,tension-type headache and other secondary headache disorders; 4. Pregnancy and lactation women; 5. Combined with hepaticrenal hematopoietic system and other serous primary diseases ,hypertension and diabetes mellitus; 6. Having severe mental disease; 7. Allergic constitution; 8. Refused to sign the consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the duration of migraine attack;change in the frequency of migraine attack;Headache days(days with more than 4h of headache irrespective of pain quality and associated symptoms);Migraine days (days with typical features of migraine); | — |
Secondary
| Measure | Time frame |
|---|---|
| Automatic days;Visual Analogue Scale;Blood sugar;Glycosylated hemoglobin (HbA1C);OGTT;The frequency of analgesics;life quality of migrainers;Headache impact test;the MIgraine Disability Assesment Quetstionaire;Headache accompanied symptoms; | — |
Countries
China
Contacts
Public ContactYashuang Zhao
Harbin Medical University
Outcome results
None listed