aplastic anemia
Conditions
Interventions
A:Cyclosporin
B:Cyclosporin and Stanozolol
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with Non-severe aplastic anemia do not rely on transfusion; 2. Patients with Severe aplastic anemia or Non-severe aplastic anemia relying on transfusion have no condition treated with HSCT or ATG; 3. Aged between 18 to 65 years old; 4. Have not history of cyclosporin, androgens, HSCT or other immunosuppressants treatment; 5. Sign the informed consent document.
Exclusion criteria
Exclusion criteria: 1. With severe organ dysfunction or diseas, such as heart, lung, kidney,pancreas; 2. WIth active hepatitis, syphilis and HIV; 3. Any cause of abormal liver function, grater than twice the normal in ALT/AST or TBIL; 4. ECOG score >2; 5. Pregnant patients; 6. Congenital hematopoietic failure; 7. Uncontrolled infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood routine;bone marrow exmination;blood biochemistry;Cyclosporine blood concentration; | — |
Countries
China
Contacts
Public ContactYingmei Li
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed