Severe Osteoarthritis KneeArthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) ASA physical status 1 to 3; (2) Aged 50-75 years old; (3) Patients were sheduled for unicompartmental knee arthroplasty surgery under Intrathecal Anesthesia.
Exclusion criteria
Exclusion criteria: (1) Severe cardiovascular disease; (2) Significant renal or hepatic impairment; (3) History of drug and alcohol abuse; (4) Patients cannot cooperation; (5) Preoperative coagulation dysfunction; (6) Allergies to local anesthetics or dexmedetomidine; (7) Peripheral nerve injury or underlying injury.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Worst pain during movement in the operated knee during first 24h postoperative; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time from the end of surgery until breakthrough pain;;NRS score at rest;NRS score during movement;Dose of rescue medicine;Time Up & Go Test;10 m Walk;30s Chair Stand test;Ambulation distance at discharge;Maximum flexion at discharge;Length of hospital stays; | — |
Countries
China
Contacts
the Department of Anesthesiology and Operating Theatre, Xuanwu Hospital of Capital Medical University