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Study of large dose statin on post myocardial infarction depression

Regulation of interleukin 1ß by low density lipoprotein-induced Jmjd3 involves in the mechanism of post-myocardial infarction depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008618
Enrollment
Unknown
Registered
2016-06-09
Start date
2017-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post- myocardio infarcyion depression

Interventions

control group:Atorvastatin calcium 20mg/d
experimental group :Atorvastatin calcium 40mg/d

Sponsors

Tongji Hospital of Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) Myocardial infarction is diagnosed according to the 3rd version of global definition of myocardial infarction published by the ESC/ACCF/AHA/WHF in 2012

Exclusion criteria

Exclusion criteria: 1. Any history of depression or other psychiatric disease; 2. Cognitive impairment; 3. Severe renal or hepatic dysfunction; 4. Co-existed anxiety; 5. Left ventricle ejection fraction less than 0.45; 6. Allergic to statin or any statin taken history; 7. Acute or chronic inflammatory disease; 8. Hypothyroidism.

Design outcomes

Primary

MeasureTime frame
gene expression profiling;IL-1ß;—

Countries

China

Contacts

Public ContactWenlin MA

Tongji Hospital of Tongji University

mawenlin@tongji.edu.cn+86 18621892703

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026