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The dose-effect of Dexmedatomidine on the electrical activity of subthalamic nucleus neuron and the clinical effect of dexmedatomidine on the Parkinson’s patient

The dose-effect of Dexmedatomidine on the electrical activity of subthalamic nucleus neuron and the clinical effect of dexmedatomidine on the Parkinson’s patient

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008464
Enrollment
Unknown
Registered
2016-05-12
Start date
2016-05-03
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson' disease

Interventions

DEX Group:Dexmedatomidine
Control group:none

Sponsors

Xuanwu Hospital of Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: the parkinson' disease patients who undergo bilateral deep brain stimulation

Exclusion criteria

Exclusion criteria: 1. BMI=30kg/m2; 2. chronic obstructive pulmonary disease; 3. coronary heart disease; 4. diabetes mellitus; 5. Second degree and third degree atrioventricular block; 6. Hepatic and renal functions abnormality; 7. patients refuse participation the study.

Design outcomes

Primary

MeasureTime frame
bispectral index;Microelectrode record of subthalamic nucleus;—

Secondary

MeasureTime frame
Blood pressure;Heart rate;pulse oxygen saturation;Ramsay score;end tidal carbon dioxide pressure;—

Countries

China

Contacts

Public ContactLIU QINGHAI

Xuanwu Hospital of Capital Medical University

xwyylqh@163.com+8613811177014

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026