Insomnia
Conditions
Interventions
Treatment group:Take Suanzaoren Decoction granules for 4 weeks
control group:take Placebo for 4 weeks
Sponsors
Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients with malignant tumor diagnosed by pathology or cytology(clinical diagnosis was adequate for hepatocellular carcinoma and pancreatic cancer); (2) According with the diagnosis of insomnia; (3)Aware of the purpose of this study, and voluntary cooperation, can truthfully and actively assess their psychological status; (4) No previous history of mental illness; (5) Without taking psychotropic substance abusers in nearly two weeks; (6) Not associated with other medical diseases; (7) KPS score 60 points or more and is expected to survive longer than six months.
Exclusion criteria
Exclusion criteria: (1) Concomitant severe primary heart, brain, liver, kidney and/or hematopoietic system disease, severe complications and comorbidities caused by the cancer, including insomnia caused by cancer pain; (2)Takehypnotic, anxiolytic, antidepressant tablets or other decoction contained semen 2 weeks before join this clinical trials; (3) Pregnancy, breast-feeding women; (4) The certain drug in the prescription allergy; (5) Psychiatry, severe anxiety, depression with SAS, SDS score>=50points; (6) Not medication on time, poor compliance or not adhere to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index PSQI;serotonin;norepinephrin;dopamine;melatonin;CD4+,CD8+,CD4+/CD8+;natural killer cell;interleukin- 6; | — |
Secondary
| Measure | Time frame |
|---|---|
| SAS;SDS; | — |
Contacts
Public ContactYang Xue
Changhai Hospital of Traditional Chinese Medicine, Second Military Medical University
Outcome results
None listed