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Clinical study on Shenzhu Guanxin Recipe improving the resistance of clopidogrel in patients with elective percutaneous coronary intervention

Clinical study on Shenzhu Guanxin Recipe improving the resistance of clopidogrel in patients with elective percutaneous coronary intervention

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008386
Enrollment
Unknown
Registered
2016-04-28
Start date
2016-05-03
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. coronary heart disease and pci successful; 3. the platelet inhibition rate was less than 10% after clopidogrel loading 24h; 4. a syndrome of qi deficiency with phlegm and blood stasis on the day of pci; 5. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Clopidogrel within 10 days; 2. Aspirin clopidogrel and heparin allergy; 3. With severe disease, the estimated survival time is less than 1 years; 4. Clear peptic ulcer and taking omeprazole or lansoprazole; 5. Suffer from acute and chronic blood disease, hemorrhagic disease, or platelet count < 100*10^9; 6. With severe liver and kidney damage or infection, tumor, immune system disease; 7. Stop Tirofiban Hydrochloride less than 12 hours; 8. A false resistance caused by inadequate measurement of clopidogrel; 9. Pregnant women or women of childbearing age having fertility requirements; 10. Mental disorders or cognitive dysfunction; 11. Expected poor compliance, not in accordance with the requirements of the patient diary card; 12. Participated in other clinical trials in the last 3 months; 13. Other conditions not suitable for of the trial.

Design outcomes

Primary

MeasureTime frame
Platelet aggregation rate;PAC-1;CD62p;PLA;

Secondary

MeasureTime frame
Standards of TCM symptoms;CRP;Carotid artery ultrasonography;electrocardiogram;MACE;

Countries

China

Contacts

Public ContactHuanlin Wu

Guangdong Provincial Hospital of Chinese Medicine

wuhuanlinboshi@aliyun.com+86 13822212111

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026