Skip to content

Feasibility study of target controlled PEEP to reduce pulmonary shunt in one lung ventilation

Feasibility study of target controlled PEEP to reduce pulmonary shunt in one lung ventilation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-16008292
Enrollment
Unknown
Registered
2016-04-16
Start date
2016-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Diseases

Interventions

A:According to the P-V ring low inflection point +2 set PEEP
B:According to the P-V ring titration method set PEEP
C:According to the lung static compliance titration method set PEEP
D:According to the lung dynamic compliance titration method set PEEP

Sponsors

Shanghai General Hospital,Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Selected Shanghai 75 patients undergoing thoracic surgery of unilateral lobectomy patients in the first people's Hospital, male or female, aged 18-70 years old, ASA I ~ II, body mass index 20~28Kg/m2. By test patients within the past week there is no history of pulmonary infection, thoracic and abdominal abnormalities, cardiovascular disease in compensatory stage, does not cause hemodynamic changes in lung tissue fibrosis, preoperative pulmonary function tests: Min maximal ventilatory volume (MVV) measured value / predictive value > 70%, the first second forced expiratory volume accounted for a percentage of the forced vital capacity (FEV1) measured / predicted values%.

Exclusion criteria

Exclusion criteria: Patients within the past week has a history of lung infection, thorax and abdominal abnormalities and cardiovascular disease will cause the change of hemodynamics, pulmonary fibrosis, and preoperative pulmonary function tests: Min maximal ventilatory volume (MVV) measured value / predictive value < 70%, the first second forced expiratory volume accounted for forced lung activity percentage (FEV1) measured value and predicted value less than 60%.

Design outcomes

Primary

MeasureTime frame
Lung shunt;

Countries

China

Contacts

Public ContactChen Lianhua

Shanghai General Hospital south courtyard anesthesia

chenlianhua1991@aliyun.com+86 13301978757

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026