Periodontal Disease, Periimplant Disease
Conditions
Interventions
1/2/3:Crossover- Active - Placebo
Sponsors
Nikos Mattheos
Eligibility
Sex/Gender
Male
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Systemically healthy, non-smoker adult subjects (30-65 years) will recruited into 3 groups as follows: Group1: Diagnosed as having generalized chronic periodontitis (CP); Group2: Diagnosed as periodontally healthy controls (H); Group3: Partially edentulous and have received implant therapy, with periimplant health and ready to receive a definitive prosthesis. (I)
Exclusion criteria
Exclusion criteria: 1. A recent history of trauma or tooth extractions; 2. Pregnant or lactating females; 3. Diagnosis of periimplantitis (PD >=5mm with signs of supporting bone loss); 4. Implant sites treated with augmentation procedures; 5. Subjects who underwent antibiotic therapy within past 3 months; 6. Radiation therapy in the head and neck area, HIV, Tuberculosis, hepatitis or other infectious diseases or uncontrolled diabetes, ischaemic heart disease, thyroid disorders or psychological problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbiome Analysis;Microbiome Analysis; | — |
Countries
India
Contacts
Public ContactNikos Mattheos
Faculty of Dentistry, University of Hong Kong
Outcome results
None listed