knee osteoarthritis
Conditions
Interventions
moxa 1 group:moxibustion with moxa from Qichun, Hubei province
moxa 2 group:moxibustion with moxa from Nanyang, Henan province
non-moxa group:moxibustion with Herba Artemisiae Capillariae
Sponsors
Acupuncture and moxibustion hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 50 to 80 years; (2) Meeting the diagnostic criteria of primary knee osteoarthritis; (3) The Womac osteoarthritis index scores at total of 48 to 72, rated as a moderate to severe disease grade, after the stop of drugs for knee osteoarthritis (including non-steroidal anti-inflammatory drugs, analgesic, Chinese herbs or Chinese patent medicine) for 3 days; (4) The Kellgren and Lawrence grades of knee osteoarthritis is grade 2 or grade 3.
Exclusion criteria
Exclusion criteria: (1) Secondary knee osteoarthritis; (2) The target knee joint had a history of trauma or surgery in the recent year , or had severe deformity; (3) The target knee joint was received intra-articular injection of corticosteroid in the past three months, or received intra-articular injection of sodium hyaluronate, acupuncture or moxibustion in the past two weeks; (4) Symptomatic hip osteoarthritis or patella osteoarthritis in the same side as the target knee joint; (5) Inflammatory or other rheumatic disease; (6) Acute meniscus injury of knee joint, or acute ligamentous injury or rupture of knee joint; (7) Tumor, tuberculosis or spontaneous osteonecrosis of knee joint; (8) Patients who have to take paracetamol, non-steroidal anti-inflammatory drug or analgesic for the control of other diseases; (9) Uncontrolled hypertension or diabetes, or serious cardiovascular, cerebral, lung, liver, kidney, or hematopoietic system disease, malignant tumor, hemorrhagic disease, or psychiatric disease; (10) Scar diathesis or cutaneous sensory disorder; (11) Pregnant or lactating women; (12) Patients who refuse to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC pain score;VAS score of knee pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total score, stiffness subscale score and physical function subscale score of WOMAC;proportion of patients acheiving clinical improvement;general assessment of patients;amount of articular effusion in knee joint; | — |
Countries
China
Contacts
Public ContactHong Zhao
Outcome results
None listed