herpetic neuralgia
Conditions
Interventions
experimental group:short-term spinal cord stimulation
control group:continuous epidural block
Sponsors
The First Affiliated Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Understand and voluntarily endorse informed consent; 2. Male or female and 60 years of age or older; 3. patients presented with Herpes zoster within 4 months from the rash onset; 4. Pain(rash site)is located between Thoracic 1 to Lumbar 5; 5. patients self-reported moderate to severe pain related to zoster (VAS>=4); 6. subjects who can be able to follow the follow-up plan; 7. Patients who can objectively describe the symptoms, can take the initiative to cooperate, without any mental illness.
Exclusion criteria
Exclusion criteria: Subjects complying with any of the following exclusion criteria are not eligible to participate in this study: 1. Spinal deformity or intolerance to the epidural catheterization; 2. Serious organ damage, such as CHF (congestive heart-failure), patients with clinical symptoms of coronary artery disease and arrhythmia uncontrollable by existing medicines, etc.; 3. Past history of severe cerebrovascular disease; 4. Patients with allergic diseases, allergic constitution, drug allergic history (gabapentin, oxycodone and acetaminophen); 5. Patients with intracranial metastases and consciousness disorders; 6. Central infection, severe systemic infection; 7. Coagulation dysfunction; 8. Subarachnoid space obstruction; 9. patients with severe peptic ulcer, pancreatitis, intestinal obstruction, asthma and other contraindications related to the test drugs; 10. Patients in other clinical research at the same time; 11. The patients that researchers do not consider fit for the trial; 12. Pregnancy or breast-feeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Reduction (Visual Analogue Scale, VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of analgesic;Quality of Life (The 36-item version of Short Form Health Survey);Daily sleep interference score(SIS);Douleur Neuropathique 4 questions;Complications of entire follow-up period; | — |
Countries
China
Contacts
Public ContactSong T
The First Affiliated Hospital of China Medical University
Outcome results
None listed