Knee osteoartritis
Conditions
Interventions
Controlled group :no hypnotics
Sponsors
Department of Orthopaedics, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
22 Years to 88 Years
Inclusion criteria
Inclusion criteria: 1. Primary unilateral total knee artropasty; 2. Patients with Knee osteoartritis or Rheumatoid arthritis; 3. Able and willing to provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Simultaneously bilateral total knee artropasty or revision case; 2. Surgical History of the knee joint; 3. Knee joint cavity paracentesis in recent 3 months; 4. Stiffness with knee; 5. Blood coagulation disorders; 6. History of deep venous thrombosis; 7. Concomitant medical problems such as uncontrolled hypertention, severe cardiovascular disorder, chronic obstructive pulmonary disease, liver or renal failure 8. allergic to NSAIDs, opioid analgesics, zolpidem 9. sleep apnea, Parkinson disease, dementia, depression 10. use of sedatives or hypnotics 11.inability to comply with polysomnographic measurement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Range of motion;VAS;polysomnographic measurement;Insomnia severity index;PSQI;GAD-7;WOMAC;; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood transfusion volume;Blood transfusion cases;Hb;Hct;Dressing change;Length of hospital stay;KSS;VAS satisfaction;Swelling;Quadriceps strength;ESR;CRP;SF-12; | — |
Countries
China
Contacts
Public ContactZhou Zongke
Outcome results
None listed