colorectal cancer
Conditions
Interventions
Tharapy:Zuojin partical
Control:placebo
Sponsors
Shuguang Hospital affiliated with Shanghai University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) clear cytology or pathological diagnosis of colorectal cancer patients; (2) all gender, aged 18 to 75 years old; (3) body condition scoring KPS 80 or higher.Expected survival period of 6 months or more; (4) for clinical stage IIb - IV to do chemotherapy, biopsy and/or peripheral blood test P - gp protein is positive, the diagnosis of multiple drug resistance of colorectal cancer patients; (5) Always have repeatedly chemotherapy, and 6 months in patients with recurrence or metastasis; (6) No serious heart, liver, kidney, hematopoietic system disease, and other factors affecting drug evaluation; Observe all landowners voluntarily accept this study plan, good adherence, clear-thinking, clearly stated, language and sensory response to normal; (7) Understanding the situation of this study and signed informed consent, to follow-up.
Exclusion criteria
Exclusion criteria: Have any of the following items are not included in this test: (1) does not conform to the diagnosis and inclusion criteria, diagnosis unknown;Pathological types for non epithelial tumors such as stromal tumor, colon malignant melanoma, colon smooth muscle sarcoma, etc.; (2) has serious heart disease of cardiovascular system, urinary system diseases, diseases of the blood system, digestive system disease, can't tolerate the patients clinical trials; Women during pregnancy or lactation;Mental disorders are not easy to control; (3) observed during disease progression, life-threatening, patients can't cooperate with the follow-up; (4) no detection, with poor adherence, patients lost to follow-up, to give up treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS;overall response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| resistance protein;quality of life;TCM symdrom; | — |
Countries
China
Contacts
Public ContactZHAO Gang
Outcome results
None listed