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Observe the Synchronism of Brain Network-Gene Expression in Treating Depression with Electro-acupuncture

Observe the Synchronism of Brain Network-Gene Expression in Treating Depression with Electro-acupuncture

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15007551
Enrollment
Unknown
Registered
2015-12-10
Start date
2016-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

acupuncture+medicine:acupuncture and Escitalopram
acupuncture+placebo:acupuncture
medicine:Escitalopram

Sponsors

Peking University Sixth Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Conforms to the international classification of diseases (ICD-10) mild and moderate depression (F32) diagnostic criteria, and exclude other mental disorder through MINI,diagnosed for the first time, without system treatment, course 2 weeks - 1 year; 2. HAMD-24 score is >=20 and <35; 3. Age above 18 and under 65; 4. Informed consent and volunteer subjects.

Exclusion criteria

Exclusion criteria: 1. Four weeks before the start of this study had participated in other clinical trials; 2. Taking or 2 weeks before the start of this test was taking antidepressant medication; 3. Brain disease, abnormal judgement ability (Wechsler Adult Intelligence Scale is less than 90 points); 4. The system with other serious diseases need to be treated; 5. With apparent suicide intend; 6. Suffer from other mental disorders.

Design outcomes

Primary

MeasureTime frame
HAMD-24;

Secondary

MeasureTime frame
QIDS-SR16;HAMA;BPI;SSRS;SF-36;MASS;Quantization Table for TCM Syndrome Differentiation;C-SSRS;SERS;CGI;Patient satisfaction questionnaire;fMRI;Depression related mRNA;IL-1;IL-6;TNF-alpha;ACTH;CORT;CRH;

Countries

China

Contacts

Public ContactTu Ya
tuyab_tcm@163.com+86 67287822

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026