Mild Cognitive Impairment after cerebral infarction
Conditions
Interventions
acupuncture group:acupuncture
the combination group of acupuncture with Nimodipine:acupuncture and Nimodipine
Sponsors
First teaching hospital of Tianjin University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Comply with mild cognitive impairment after cerebral ischemia diagnostic criteria; 2. Consistent with CDR and no more than 0.5 points; 3. score of MOCA is in line with standard of cognitive impairment,and 7; 6. Weighing between 50 ~ 90kg, aged 50 to 80 years, both men and women; 7. Within ischemic stroke for at least two weeks to six months; 8. Muscle is 3 or above, no language barriers; 9. There is a certain level of education, previous to read simple newspaper articles and write simple little article; 10. Volunteer who have good compliance and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. In line with the diagnosis of dementia.There is manifestation of memory impairment or other cognitive dysfunction in early stage, and progressive increase. Imaging is no corresponding ischemic lesions; 2. Cognitive impairment by a reason other than the cause of cerebral infarction,such as Cerebral hemorrhage, encephalitis, epilepsy, cancer, multiple sclerosis, mental illness, hypothyroidism, alcohol or drug abuse. People who has severe vision, hearing impairment, severe aphasia or limb weak and effect the inspection; 3. Suffering from certain diseases can interfere with cognitive function evaluation, like alcoholics, a cognitive impairment caused by head injury, to be addicts over the past 5 years by the standard of DSM-IV or Other psychotropic drugs abusers; 4. Depression or other mental disorders; 5. There are other diseases, especially liver, kidney or heart failure, like the ALT or AST in more than three times normal, Scr>177Lmol, or Heart function 2 to 4, HR110, people who had myocardial infarction or fatal arrhythmias before 4 months of participating in the trial; 6. Other diseases that can cause cognitive impairment, like Cancer, thyroid dysfunction, syphilis and severe anemia patient; 7. Patients with uncontrolled diabetes. Asthma and chronic obstructive pulmonary disease. Patients with multiple neuritis. Patients with myasthenia gravis and amyotrophic. Glaucoma patients. Severe indigestion, gastrointestinal obstruction or ulcer of stomach and duodenal and other gastrointestinal disorders that can affect drug absorption; 8. Over the past 30 days had used similar medications, such as taking over related or antagonistic effects of drugs, so that the efficacy of the drug is difficult to judge; 9. Have allergy to the drug of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| MOCA;Neuropsychiatric Inventory;Activity of daily living scale;functional activities questionnaire;SDSVD;FAQ; | — |
Countries
China
Contacts
Public ContactJiangang zheng
Outcome results
None listed