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FSH co-trigger with HCG improves oocyte developmental competence and clinical pregnancy rates in patients with low serum estradiol levels on the day of HCG administration undergoing in vitro fertilization treatment

FSH co-trigger with HCG improves oocyte developmental competence and clinical pregnancy rates in patients with low serum estradiol levels on the day of HCG administration undergoing in vitro fertilization treatment

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15007360
Enrollment
Unknown
Registered
2015-10-31
Start date
2015-11-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low serum estrodial level on the day of HCG trigger in controlled ovarian hyperstimulation undergoing IVF-ET treatment

Interventions

FSH co-trigger group:FSH co-trigger with HCG
Control group:HCG trigger only

Sponsors

The People's Hospital of Guangxi Zhuang Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Normal response to controlled ovarian hyperstimulation with the mid-luteal GnRH agonist long protocol in conventional IVF-ET; 2. E2 /fol>14mm Follicles <=150pg/ml on the day of HCG trigger.

Exclusion criteria

Exclusion criteria: 1. Age>=40 years old; or with diminished ovarian reserve, AMH=3500pg/ml on the day of HCG trigger; 5. Cancel cycles because of endometrium abnormality and other reasons; 6. Need to do ICSI for fertilization because of male factor, such as azoospermia, severe asthenospermia and oligozoospermia; 7. Rescue ICSI because of fertilization failure in fresh cycle.

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate;

Secondary

MeasureTime frame
Oocyte recovery rate;Fertilization rate;Implantation rate;M?oocyte rate;

Countries

China

Contacts

Public ContactWeihong Tan

The People's Hospital of Guangxi Zhuang Autonomous Region

15978132072@163.com+86 15978132072

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026