repair of bone defect in oral andmaxillofacial surgery
Conditions
Interventions
Control group:Fill extraction sockets with control bone graft
Experimental group:Fill extraction sockets with experimental bone graft
Sponsors
The Peking University School of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Men or women aged between 18-70 years old; 2. Volunteers with good oral hygiene, plaque index<i degrees, the whole gingiva bop <20%. (If the volunteers are disqualification, they can be assessed again at the time of 6 weeks after periodontal therapy.); 3. Each volunteer has one anterior tooth or one premolar tooth which is need to be extracted because of caries, periodontitis, trauma, congenital malformations, the requirement of orthodontic or prosthetics etc andthey agree to fill bone graft (calcined bovine bone) in extraction socket; 4. The remain bone mass after extraction in target area is enough to fill bone packing materials(calcined bovine bone); 5. The adjacent teeth do not suffer from serious lesion,such as periodontitis andpriepical lesion; 6. The occulusion between our impants andthe natural tooth or denture in other jaw is normal.
Exclusion criteria
Exclusion criteria: 1. Volunteers who can not obey the research procedure; 2. Volunteers who have recieved dental implantation or restoration in the research area before; 3. Volunteers with diseases that may affect healing or osseointegration; 4. Volunteers have been diagnosed or suspected with malignant tumors; 5. Volunteers have history of radiation therapy of head or neck; 6. Volunteers who have been treated with chemotherapy within five years; 7. Someone with systematic or local diseases that may have negative influence on healing or osseointegration; 8. Someone with uncontrolled metabolic diseases, such as diabetes, rickets, thyroid diseases,severe hepatic renal dysfunction, etc.; 9. Someone who are using corticosteroids or any other drugs that may have negative influence on healing or osseointegration; 10. Smoking more than 15 pieces in one day; 11. Someone who have alcoholism or drug abuse; 12. Someone who are participating in other clinical researches spontaneous or have participated within the last 6 months; 13. Someone who have mental andneurological diseases or other reasons so that they can not provide informed consent.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Variation values in vertical distance of the alveolar ridge over 6 months;the level of bone healing at the extraction site; | — |
Primary
| Measure | Time frame |
|---|---|
| Variation values in horizontal distance of the alveolar ridge over 6 months; | — |
Countries
China
Contacts
Public ContactZhihui Tang
Outcome results
None listed