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Comparison of sedation regimens using etomidate andpropofol during colonoscopy:A prospective randomized clinical trial

Comparison of sedation regimens using etomidate andpropofol during colonoscopy:A prospective randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15007178
Enrollment
Unknown
Registered
2015-09-21
Start date
2015-09-21
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

digestive diseases

Interventions

SP:sufentanil 0.1 ug/kg+propofol1 mg/kg induce, propofol 0.5mg/kg every time maintain
SEP:sufentanil 0.1 ug/kg+etomidate 0.2mg/kg induce, propofol 0.5mg/kg every time maintain
SPE:sufentanil 0.1 ug/kg+propofol1 mg/kg induce, etomidate 0.1mg/kg every time maintain
SE:sufentanil 0.1 ug/kg+etomidate 0.2mg/kg every time maintain

Sponsors

epartment of anesthesiology,West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included patients aged 18-65 years who scheduled to undergo colonoscopy within 60 min, gender not limited, Body mass index (BMI) 18.5 ~ 30 kg/m2,ASA I-III.

Exclusion criteria

Exclusion criteria: Exclusion criteria included cardiac, pulmonary, hepatic or nephritic disease, metabolic disease,abnormal anesthesia recovery, acute airway inflammation in the past 2 weeks,blood pressure >180/110 mmHg and/or diastolic blood pressure > 110 mmHg, or blood pressure < 90/60mmHg, neuromuscular disease, Hemoglobin is less than 70 g/L,possible or happened difficult airway, allergy to emulsion or opioid, hormones or adrenal cortex inhibitors over 3 weeks, electrolyte disturbance.

Design outcomes

Primary

MeasureTime frame
mean arterial pressure;leaving time;

Secondary

MeasureTime frame
heart rate;Pulse oximetry;Onset time;recovery time;

Countries

China

Contacts

Public ContactXiao Wang
1490829116@qq.com+86 18980601549

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026