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Effect andEfficacy of a Linoleic Acid-Ceramide Containing Moisturizer in pruritus hiemalis

Effect andEfficacy of a Linoleic Acid-Ceramide Containing Moisturizer as an adjunctive therapy in the treatment of pruritus hiemalis:A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15007137
Enrollment
Unknown
Registered
2015-08-31
Start date
2003-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pruritus hiemalis

Interventions

Control Group:mometasone furoate 0.1% cream once daily

Sponsors

Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Clinically Diagnosed pruritus hiemalis patients; 2. No age limitation; 3. No limitation on gender; 4. Participant or legal guardian fully understands the content of the clinical trial, is willing to attend the research voluntary andsign the informed consent form; 5. Physical examination is qualified, participant does not have previous severe systemic disease.

Exclusion criteria

Exclusion criteria: 1. other skin diseases; 2. physical examination failed to qualify for enrollment; 3. during gestational andlactation period; 4. known allergic history toward drug or moisturizer under study; 5. involved in any other clinical trial three months before enrollment; 6. frequently usage of herbal, hypnotics, sedative, stabilizers, or other addictive medication; 7. alcoholics, psychotic, or participants who cannot follow prescription order; 8. Utilization of any types of skin moisturizers or topical medications within one-month prior to the screening andduring the study period; 9. systemic therapies or phototherapy previously within three months of screening andduring the study period.

Design outcomes

Primary

MeasureTime frame
dryness;Pruritus;

Secondary

MeasureTime frame
skin capacitance;skin transepidermal water loss;

Countries

China

Contacts

Public ContactJie Zheng
jie-zheng2001@126.com+86 18917762309

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026