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A prospective randomized study of acupuncture combined with IVF-ET on pregnancy outcome its associated mechanisms

A prospective randomized study of acupuncture combined with IVF-ET on pregnancy outcome its associated mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15007061
Enrollment
Unknown
Registered
2015-08-28
Start date
2015-10-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

acupuncture arm:acupuncture+IVF-ET

Sponsors

Nanjing General Hospital of Nanjing Military Area Command
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Compliance with IVF-ET inclusion criteria; 2. the patient had undergone IVF-ET more than once but do not successful embryo implantation; 3. Vaginal B super ovulation confirmed ovulation occurs; 4. Aged <= 40 years old; 5. According to the foundation of the state of ovarian, patients accept controlled ovarian hyperstimulation programs; 6. Signed informed consent, voluntary acceptance of two courses of treatment examination; 7. Not taking any hormones other drugs were within the first month of treatment.

Exclusion criteria

Exclusion criteria: 1. Contraindicated in patients with IVF-ET; 2. Failing to treat, can not determine the efficacy of other factors; 3. Who is participating in other clinical trials; 4. Serious primary disease with cerebral vascular, cardiovascular, liver, kidney hematopoietic tem; mental illness; blood glucose control in diabetic patients.

Design outcomes

Primary

MeasureTime frame
Biochemical pregnancy rate;Clinical pregnancy rate;Live birth rate;Vaginal B ultrasound;Gene expression profile of endometrial tissue;mRNA and protein expression of target gene;Estrogen receptor;Progesterone receptor;Vascular endothelial growth factor;IL-11;Leukemia inhibitory factor;C-reaction protein;miRNA;

Secondary

MeasureTime frame
Serum sex hormone levels;Biological and safety indicators;

Contacts

Public ContactYoubing Xia
xybd1968@sina.com+86 18061661008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026