Pediatric sedation on ophthalmic examinations
Conditions
Interventions
Chloral hydrate:oral 80 mg/kg of Chloral hydrate
Dexmedetomidine:Intranasal 2 µg/kg of dexmedetomidine
Sponsors
Zhongshan Ophthalmic Center, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: (1) Need sedation for ophthalmic examinations; (2) With informed consent from the parents.
Exclusion criteria
Exclusion criteria: (1) Children with gastroesophageal reflux; (2) Children with nausea and vomiting; (3) Children with apnea in the past three months; (4) Children with recent pneumonia, exacerbation of asthma, bronchitis and upper respiratory tract infection; (5) Children with severe arrhythmias, heart failure and cardiac structural abnormalities; (6) Children with facial abnormalities, who is expected to be difficult with effective mask ventilation; (7) Children with severe neurological disease; (8) Children with moyamoya disease; (9) Children who is allergy for dexmedetomidine or chloral hydrate; (10) Children who were enrolled in the present study previously; (11) Preterm children, weight <2 kg, or age <2 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful sedation;Nausea vomitting;Respiratory depression;appetite; | — |
Secondary
| Measure | Time frame |
|---|---|
| Examination time;Awake time;Discharge time; | — |
Countries
China
Contacts
Public ContactXiaoliang Gan
Outcome results
None listed