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Effects of hemodiafiltration versus hemodialysis on endothelial dysfunction in maintenance hemodialysis patients

Effects of hemodiafiltration versus hemodialysis on endothelial dysfunction in maintenance hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15006961
Enrollment
Unknown
Registered
2015-08-24
Start date
2010-02-25
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease

Interventions

two:hemodialysis and hemodiafiltration

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included patients being on low-flux HD thrice a week for 6 months, with well functioning native AV fistulas for blood access , haemoglobin level ranging between 10 and 13 g/dL in the previous 3 months, stable with a minimum dialysis single-pool Kt/V for urea >=1.2.

Exclusion criteria

Exclusion criteria: Exclusion criteria included any acute illness such as infection or cardiovascular event (i.e., acute myocardial infarction) or cerebrovascular (i.e., ischemic stroke) event within the past month, severe hypertension (systolic blood pressure >180 or diastolic blood pressure >110 mmHg), current estrogen / hormone replacement therapy or intravenous ferrum or oral antiplatelet durgs (such as aspirin, etc.)

Design outcomes

Primary

MeasureTime frame
flow-mediated dilatation (FMD%);soluble endoehelial protein C receptor;soluble thrombomodulin;interleukin-6;high sensitive C-reactive protein;

Countries

China

Contacts

Public ContactTeng Jie
ding.xq@zs-hospital.sh.cn+86 13761732850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026