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Research of active lactobacteria modified intestinal flora in the patients with alcoholic liver disease and potential mechanisms

Research of active lactobacteria modified intestinal flora in the patients with alcoholic liver disease and potential mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15006806
Enrollment
Unknown
Registered
2015-07-24
Start date
2015-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alcoholic liver disease

Interventions

control:placebo
group 1:Active lactobacillus100 g/d
group 2:Active lactobacillus200 g/d

Sponsors

Qingdao University Medical College
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) conform to the alcoholic liver disease diagnosis and treatment guidelines (revised in 2010); (2) alcohol during treatment; (3) can insist on 1 months of treatment, and complete the main observation indexes;

Exclusion criteria

Exclusion criteria: (1) the age under 18 years or 75 years old or above; Pregnancy or lactation women; (2) during treatment recurrence drinkers; (3) with severe complications such as cardiovascular, liver and hematopoietic system, cancer of the liver or to the merger; (4) psychiatric patients cannot partners; (5) does not meet the inclusion criteria, not according to stipulations, unable to judge the curative effect or data not congruent effect judging efficacy or safety.

Design outcomes

Primary

MeasureTime frame
Liver function;blood lipids;Plasma endotoxin levels;ERIC - PCR fingerprint intestinal flora;16 s rDNA real-time fluorescent quantitative PCR analysis of changes of intestinal flora;

Countries

China

Contacts

Public ContactLiang Hui
qdlianghui@126.com+86 18615329686

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026