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Study on the improving effects and the mechanisms of Omega-3 polyunsaturated fatty acids combined with folic acid and vitamin B6 on atherosclerosis

Study on the improving effects and the mechanisms of Omega-3 polyunsaturated fatty acids combined with folic acid and vitamin B6 on atherosclerosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15006804
Enrollment
Unknown
Registered
2015-07-24
Start date
2015-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerosis

Interventions

control:placebo
group 1:fish oil (EPA+DHA620mg/d)
group 2:0.4mg/d folic acid+ 10.0 mg/dVB6
group3:0.4mg/d folic acid+ 10.0 mg/dVB6+fish oil (EPA+DHA620mg/d)

Sponsors

Qingdao University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Patients with the WHO diagnostic criteria for diagnosis of coronary heart disease (CHD) or by coronary angiography showed a major coronary arteries or multivessel coronary vascular stenosis greater than or equal to 50%; 2) Patients of screening in the first two months not taking omega-3 fatty acids, vitamins and minerals and other supplements; 3) Patients of voluntarily signed informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients of severe liver and kidney disease, tumor, and peripheral vascular disease, recently had surgery and trauma patients; 2) Patients of complicated with other diseases, and researchers believe that affect curative effect evaluation or compliance claim; 3) Patients of any other reason, the researchers think not appropriate participants.

Design outcomes

Primary

MeasureTime frame
blood lipids;Inflammatory factors;The cell signaling pathways of protein expression;

Countries

China

Contacts

Public ContactLiang Hui
qdlianghui@126.com+86 18615329686

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026