Meibomian Gland Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients should meet MGD-Stage 2-3 according to the 2011 International Workshop on MGD. The diagnostic criteria are as follows: (1) symptoms of ocular discomfort: itching, or photophobia with limitations of activities; (2) clinical signs: one lid margin feature (plugging, vascularity) at least, meibum quality: grade >=4-<13, expressibility: 1-2, corneal staining: 0-10. Only the involved eye or the right eye will be enrolled.
Exclusion criteria
Exclusion criteria: (1) Previous ocular surgery or trauma; (2) allergic to fumigation treatment; (3) systemic diseases or treatments that may affect the quality and stability of tear film.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Break-up time (BUT);cornea staining;MGD grading;meibum quality;meibomian gland expressibility; | — |
Secondary
| Measure | Time frame |
|---|---|
| Schirmer I test;Ocular surface disease index (OSDI); | — |
Countries
China