End stage renal disease, maintenance hemodialys
Conditions
Interventions
Conventional HD group:4 hours per HD session, three time per week
Extended HD group 1:4.5 hours per HD session, three time per week
Extended HD group 2:5 hours per HD session, three time per week
Extended HD group 3 :6 hours per HD session, three time per week
Sponsors
Zhongda Hospital, Southeast University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Adult patients (>=18 years) with end stage renal disease recieving maintaince hemodialysis three times per week and 4-4.5 hours per session for >=6 months; 2) Signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Unable or unwilling to follow the study protocol for any reason; unable or unwilling to provide informed consent; 2) Malignant neoplastic disease; 3) Severe liver dysfuction; 4) Pregnant and lactating women; 5) Scheduled for kideney transplantation, change to peritoneal dialysis; 6) Other conditions that researchers considered unsituable for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The composite of all-cause mortality or non-fatal cardiovascular event; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality;Cardiovascular mortality;Unstable angina;Myocardial infarction;Congestive heart failure;Stroke;Change in blood pressure during two-year follow-up;Change in blood pressure variability during two year follow-up;Change in serum CRP during two year follow-up;Change in serum IL-6 during two year follow-up; | — |
Countries
China
Contacts
Public ContactBi-Cheng Liu
Outcome results
None listed