Colorectal Cancer
Conditions
Interventions
Dexmedetomidine:Dexmedetomidine 1ug/kg iv.pump
Control:Same dose of NS iv.pump
Sponsors
Anesthesiology Department of the Third Afflicated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. To obtain informed consent; 2. Aged 18 to 75 years old; 3. Weight withiin 50 ~ 80 kg; 4. ASA Class I - II.
Exclusion criteria
Exclusion criteria: 1. The merger has confirmed other important organ damage: including liver and kidney dysfunction, abnormal heart function, blood coagulation dysfunction; 2. The patients with bone metastasis and distant metastasis; 3. History of nerve, mental illness, long-term use of sedative drugs, or for other reasons should not be partners; 4. Atrioventricular block, sick sinus syndrome patients with sinus bradycardia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anus exhaust time;Defecating time;Time of intake;Length of hospitalization;Quality of sleep;Diamine oxidase, DAO;Intestinal fatty acid binding protein, L-FABP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Agitation score in Awakening Period;Postoperative pain scores;Nausea and vomiting;5-yr prognosis; | — |
Countries
China
Contacts
Public ContactZhou Shaoli
The Third Afflicated Hospital of Sun Yat-sen University
Outcome results
None listed