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The median effective concentration (EC50) of propofol with different doses of fentanyl during colonoscopy in elderly patients

The median effective concentration (EC50) of propofol with different doses of fentanyl during colonoscopy in elderly patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15006368
Enrollment
Unknown
Registered
2015-05-03
Start date
2015-05-05
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The median effective concentration (EC50) of propofol with different doses of fentanyl during colonoscopy in elderly patients

Interventions

saline control group:inject saline control
0.5ug/kg fentanyl group:inject 0.5ug/kg fentanyl
1.0ug/kg fentanyl group:inject 1.0ug/kg fentanyl

Sponsors

Department of Anesthesiology,Eastern hepatobiliary Surgery Hospital,the Second Military University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
75 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1. Aged 75~89 years old; 2. American Society Anesthesiologists physical satus (ASA) I-II patients; 3. with body mass index (BMI) 19 - 27kg/m2.

Exclusion criteria

Exclusion criteria: 1. they were allergic to either propofol or fentanyl; 2. they had chronic use of analgesics; 3. they had alcohol abuse; 4. they were with neurological or pyschiatric disorders; 5. they had end stage liver or renal diseases or 6. they had Sleep Apnea Hypopnea Syndrome (SAHS).

Design outcomes

Primary

MeasureTime frame
EC50 of propofol;—

Secondary

MeasureTime frame
Hemodynamics (Heart rate/mean arterial pressure);Perioperative anesthesia related side effects;—

Countries

China

Contacts

Public ContactLiqun Yang
lqyang72721@126.com+86 15921969001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026