Heart Failure
Conditions
Interventions
Treatment group:Ultrafiltration
Sham group:Diuretics
Sponsors
Peking University First Hospital, Fu Wai Hospital CAMS&PUMC
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. More than 18 years old, male or non women, 2. Regular diuretics before admission, 3. Main on Congestive heart failure of hospitalized patients (within 24 h) , 4. the performance of the overload capacity, the performance of 2 or more items which were as follows: (1) have a lower limb or lumbosacral region refers to the pitting edema; (2) paroxysmal nocturnal dyspnea and orthopnea (>=30 degree recumbent position); (3) jugular vein engorgement >8 cm; (4) X-ray sternum with pulmonary edema, pulmonary congestion or pleural effusion. 5. signed informed consent, volunteered for the experiment.
Exclusion criteria
Exclusion criteria: 1. the acute coronary syndrome; 2. the renal insufficiency, creatinine acuity 265.8 mu mol/L (3 mg/dL), renal replacement therapy or expected; 3. systolic blood pressure, 90 MMHG or less (signed informed consent); 4. the red blood cells deposited (HCT) 45% or higher; 5. heparin anticoagulation contraindicated or heparin allergy; 6. of severe valvular stenosis; 7. the pericardial tamponade, massive pericardial effusion, pericarditis, restrictive cardiomyopathy; 8. serious with onset, expected to survive six months or less; 9. uncontrolled systemic infection; 10. potassium <3.5 tendency/L; 11. participated in any other drugs or medical devices clinical trials within 1 month; 12. during pregnancy or lactation women; 13. any mental or cognitive impairment, may limit their understanding of informed consent, execution and research the compliance; 14. the researchers believe that education is not suitable for other information to participate in this test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dyspnea score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body fluid removal;Total weight loss;NYHA heart function;NT-BNP; | — |
Countries
China
Contacts
Public ContactYong Huo, Jian Zhang
Outcome results
None listed