General Anesthesia
Conditions
Interventions
the follicular group:Dexmedetomidine is intravenously administrated at a dose of 1.0ug/kg at 10 min intervals, then continuous infusion at 0.5 ug/kg/h for 20 min.
the luteal group:Dexmedetomidine is intravenously administrated at a dose of 1.0ug/kg at 10 min intervals, then continuous infusion at 0.5 ug/kg/h for 20 min.
Sponsors
Department of Anesthesia, Obstetrics and Genecology Hospital, Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 40 female patients with regular menstrual cycles (a regular cycle was defined as lasting 25-35 days with no variations in the length of cycle of more than 2 days), ages 18–40 yr, ASA I–II, will be enrolled in the study.
Exclusion criteria
Exclusion criteria: irregular menstrual cycles; pregnancy; receiving hormones and medications that affected ovulation during the 6 weeks before surgery; chronic or acute (within 48 h) intake of psychotropic drugs; hepatic, renal, or neurological dysfunction; alcoholism or use of benzodiazepines, anticonvulsants, or opioids; In addition, those patients with a BMI 30 will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bispectral Index;progesterone;oestrogen; | — |
Countries
China
Contacts
Public ContactGE Shen-jin
Outcome results
None listed