Patients, ASA I-II scheduled for elective laparoscopic cholecystectomy, and Emergency laparoscopic appendix operation performed under general anesthesia
Conditions
Interventions
CRP normal:Ringer's solution: 20ml/kg within 35min
CRP rise:Ringer's solution: 20ml/kg within 35min
Sponsors
Shaoxing People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-60 years of age, male and female; 2. Body image index is 18-25; 3. Patients, ASA I-II scheduled for elective laparoscopic cholecystectomy, and Emergency laparoscopic appendix operation performed under general anesthesia; 4. Patients familiar with all the procedure and evaluation, agreed to participate in this experiment, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Obese patient with body image index more than 25; 2. Patients with ASA class more than grade II, severe cardiac, lung, hepatic and renal diseases; 3. Mental disorder; 4. Pregnant and breeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the parameters of distribution and elimination of Ringer’s solution; | — |
Secondary
| Measure | Time frame |
|---|---|
| The correlation between the pro-inflammatory factors (CRP and IL-1beta) and the volume kinetics of Ringer's solution;The correlation between the anti-inflammatory factors (TGF-beta 1, IL-10) and the volume kinetics of Ringer's solution; | — |
Countries
China
Contacts
Public ContactLi Yuhong
Outcome results
None listed