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Study on Optimization of Heparin Lock Concentration for Hemodialysis Patients with Central Venous Catheters

Study on Safety of Ultra-low Dose Heparin Locks on Non-tunneled Temporary Hemodialysis Catheters: A Multi-center Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15006062
Enrollment
Unknown
Registered
2015-02-16
Start date
2015-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrology

Interventions

A:common dose heparin locks(3125u/ml)
B:ultra-low dose heparin locks(500u/ml)

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age:18-90 years old;Receiving right internal jugular vein Indwelling Catheter and Operating smoothly; 2. Regular dialysis and Cooperate with collecting specimens and clinial information; 3. Patient or his/her family (guardian) agree to participate in this study, and provide written Informed Consent.

Exclusion criteria

Exclusion criteria: 1. severe heart disease as Arrhythmia, AHF, Myocardial infarction, CHF(?), Unstable angina and acute stroke; 2. with any infection in current situation, Active stage malignant tumor, Severe idiopathic diseases such as the hematopoietic system and Active TB; 3. CRRT required as the initial blood purification treatment; 4. Patient who has mental diseases and those failed to cooperate due to any reason.

Design outcomes

Primary

MeasureTime frame
coagulation function;Bleeding;—

Secondary

MeasureTime frame
Thirty-day CRI-free catheter survival;malfunction cases;service life of catheter;—

Countries

China

Contacts

Public ContactHui_Liang
1273885601@qq.com+8618929569860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026