Pain
Conditions
Interventions
A:2 ml saline is administrated via the biggest vein in the opisthenar of right hand followed by 2 mg/ Kg propofol though the same vein in 3 minutes
B:2 g lidocaine cream is wiped the opisthenar of right hand 1 hour before 2 mg/ Kg propofol is givwn
C:20 mg lidorcaine is administrated via the biggest vein in the opisthenar of right hand followed by 2 mg/ Kg propofol though the same vein in 3 minutes
D:40 mg lidorcaine is administrated via the biggest vein in the opisthenar of right hand followed by 2 mg/ Kg propofol though the same vein in 3 minutes
E:20 mg lidorcaine is administrated via the biggest vein in the opisthenar of left hand followed by 2 mg/ Kg propofol though symmetrical vein of right hand in 3 minutes
F:40 mg lidorcaine is administrated via the biggest vein in the opisthenar of left hand followed by 2 mg/ Kg propofol though symmetrical vein of right hand in 3 minutes
Sponsors
The third affiliated hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The patients are aged 18 to 60; The American society of anesthesiologists (ASA) 1 or 2; Blood routine,whose biochemicalexamination and blood coagulation are mormal, no allergy history of local anesthetic, propofol, fentanyl; No peripheral vascular disease, no chronic pain syndrome, no mental or nervous system diseases.
Exclusion criteria
Exclusion criteria: The patients have accepted painkillers or other analgesia and sedative within 24 hours; Have accepted beta-blockers, vascular active drugs or cimetidine; Have accepted drugs that cannot be companyed with lidocaine, fentanyl and propofol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| verbal rating scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure, heart rate;recovery time; | — |
Countries
China
Contacts
Public ContactHe Ziqin
Outcome results
None listed