anaesthesia
Conditions
Interventions
Group A:Patients received methylprednisolone 40mg intravenously 0.5h prior to surgery
Group B:Patients received methylprednisolone 40mg after induction of anaesthesia
Group C:Patients received normal saline 2ml
Sponsors
Obstetrics and Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Adult patients scheduled for elective gynaecological laparoscopic surgery during general anesthesia allocated to 3 groups. Their ASA physical status class were I or 1I; their ages ranged from 18 to 60 years old.
Exclusion criteria
Exclusion criteria: Patients with values outside the normal range (C-reactive protein (CRP) concentration, haemoglobin concentration, serum sodium, calcium, and potassium concentration, white cell and platelet count, serum creatinine, internationalised normalised ratio (INR), glutamicoxaloacetic transaminase (GOT), glutamic-pyruvic transaminase(GPT), gamma-glutamyl-transferase (GGT), alkaline phosphatase, bilirubin and cholinesterase); known allergies to the study drugs; pregnancy; neuromuscular disorders; intake of drugs affecting neuromuscular block such as furosemide, magnesium or cephalosporins; and hepatic or renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| onset time;clinical duration;Total duration;recovery index;recovery to a train-of-four ratio of 0.9; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood glucose;nausea and vomiting scores;the score of pain; | — |
Countries
China
Contacts
Public ContactGeng Weilian
Outcome results
None listed