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Intraveous Infusion Dexmedetomidine combined inhalation isoflurane potentiate hypoxia pulmonary vasoconstriction during one-lung ventilation via inhibiting oxidative stress

Lung protective effect of Intraveous Infusion Dexmedetomidine during one-lung ventilatio

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-15005784
Enrollment
Unknown
Registered
2014-12-23
Start date
2015-01-10
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General thoracic surgery patients

Interventions

2:Dexmedetomidine intravenous infusion

Sponsors

First Affiliated Hospital, Yangtze University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 60 General thoracic surgery patients were selected; ASA I-II, aged 18-70 years old, weighing 49-73 kg; Height 151-175 cm.

Exclusion criteria

Exclusion criteria: Long-term alcohol, opioid, or sedative; hypnotic drug addiction and dependency history, history of drug allergy, neuropsychiatric diseases.

Design outcomes

Primary

MeasureTime frame
oxidative stress;—

Countries

China

Contacts

Public ContactXia Rui
ruixia68@sina.com+86 13986738338

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026