anesthesia and analgesia
Conditions
Interventions
Dexmedetomidine Group:Patients receiving dexmedetomidine 1 ug/kg for 10 min followed by 0.5 ug/kg.h until the end of the examination
fentanyl methord group:fentanyl methord 0.6 mg/kg i.v., plus 10~20mg if necessary
Sponsors
Department of Anesthesiology, the Second Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients of either sex, aged eighteen to sixty-five years old for elective EGD procedure, with American Society of Anaesthesiologist (ASA) Grade I and II were included.
Exclusion criteria
Exclusion criteria: Patients with ASA physical status Grade III and more, prior gastrectomy, patients with comorbid conditions such as diabetes mellitus, cardiovascular disease, hepatic or renal insufficiency, history of chronic alcoholism, sedative and narcotic analgesic drug abuse; allergy to any of the drugs such as opioids, dexmedetomidine, egg or soya bean, uncooperative and pregnant patient were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Arterial Pressure;Heart Rate;Respiratory Rate;hemoglobin oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| sedation level at the mid-procedure;Sedation Levle;number of patients needed additional propofol;number of patients recovered 15 min after the procedure;number of patients recovered 30 min after the procedure;number of patients who recovered more than 30 min after the procedure;number of patients gagging;number of patients suffering bradycardia;number of patients suffering respiratory depression;satisfactory score of patients; | — |
Countries
China
Contacts
Public ContactYun Wu
Outcome results
None listed