amyotrophic lateral sclerosis
Conditions
Interventions
Chinese medicine :Jianpi Yifei Decoction
Riluzole:Riluzole
Sponsors
Guangdong Province Traditional Chinese Medical Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. At the age of 18 years old and above, not limited to men and women; 2. Meet the diagnostic criteria for ALS diagnosis / probable; 3. The patients' informed consent to accept the trial; 4. Women must not be able to become pregnant for the duration of the study. Women of childbearing potential must have a negative pregnancy test at screening and be non-lactating.
Exclusion criteria
Exclusion criteria: 1. Have allergy history of Jianpi Yifei Decoction; 2. Associated with other serious diseases including liver, kidney, cardiovascular disease; 3. Combined with mental illness or severe neurosis patients; 4. Unable to express subjective symptoms; 5. Clinical evidence of unstable medical or psychiatric illness in the investigator's judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Water swallow test;Frenchay dysarthria assessment;The ALSFRS-R scale;Swallowing angiography;Strobe laryngoscope; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;Creatinine; | — |
Countries
China
Contacts
Public ContactDu Baoxin
Outcome results
None listed