Skip to content

Prospective, randomized, controlled study comparing Ex-PRESS shunt implantation and trabeculectomy combined phacoemulsficaztion and intraocular lens implantation of primary angle-closure glaucoma with cataract

Prospective, randomized, controlled study comparing Ex-PRESS shunt implantation and trabeculectomy combined phacoemulsficaztion and intraocular lens implantation of primary angle-closure glaucoma with cataract

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-14005640
Enrollment
Unknown
Registered
2014-11-19
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary angle-closure glaucoma with cataract

Interventions

control group:trabeculectomy combined phacoemulsficaztion and intraocular lens implantation
experimental group:Ex-PRESS shunt implantation combined phacoemulsficaztion and intraocular lens implantation

Sponsors

Zhongshan Ophthalmic Center, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 50 years of age or older, in accordance with the PACG diagnosis standard; 2. lens opacity of eyes; 3. the adhesion of anterior chamber angle was more than 1/2 circle under gonioscopy; 4. pathological excavation of optic disk and defect of field vision; 5. patients agreed to accept the program and signed informed consent; 6. without any contraindications of the surgery or anesthesia.

Exclusion criteria

Exclusion criteria: 1. conjunctival scarring; 2. scar diathesis patients; 3. with rebellious infection from ocular surface; 4. IOP is more than 40mmHg after the use of ocular hypotensive agents; 5. axial length is less than 20mm (B ultrasound); 6. with heavy damage of heart, liver and kidney; heavy gastrointestinal disease; psychosis and diabetes; 7. patients with contraindication of glucocorticoid; 8. after laser operation because of glaucoma and other intraocular surgeries; 9. with secondary reasons: Len induced, neovascular and uveitis; 10. without the tolerance of the surgery and anesthesia.

Design outcomes

Primary

MeasureTime frame
intraocular pressure;vision;

Secondary

MeasureTime frame
grades of anterior angle;depth of anterior chamber;biometric parameters;corneal endothelial cells;ratio of cup to disc;visual field;retinal nerve fiber layer thinkness;pattern of filtering bleb;complications;adverse event;

Countries

China

Contacts

Public ContactMinbin Yu
yuminbin@126.com+86 13602804298

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026