Intracerebral Hemorrhage
Conditions
Interventions
the intension blood pressure reduction group :target systolic blood pressure below 140 mmHg within 1 hour
Sponsors
the first affiliated hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. aged 65-80; 2. Supratentorial hypertensive intracerebral hemorrhage; 3. hematoma volume 10-60ml; 4. Systolic blood pressure (SBP) measuring on admission is between 200mmHg-240mmHg at least two times, and the interval must be more than or equal to 2 minutes; 5. Getting to hospital within 3 hours after the symptoms occuring, GCS more than 5 on admission; 6. being voluntary to participate this trial.
Exclusion criteria
Exclusion criteria: 1. Blood pressure is more than 240mmHg onadmission; 2. Intracranial hematoma induced by trauma; 3. Having anti-hypertension treatment contraindications; 4. Having other anti-hypertension treatment indications, and the anti-hypertension treatment target is lower or equal to this study; 5. The cerebral hemorrhage is secondary to cerebral structural abnormalities; 6. Having ischemic stroke history within 30 days; 7. Having severe dementia or disablities before; 8. Prepare for an emergency surgery; 9. Having a bleeding tendency; 10. Having delivery pregnancy or lactation within 30 days; 11. Having warfarin within 5 days; 12. PLT less than 50000/mm3; 13. Having major diseases of internal medicine, which may interfere with the outcome evaluation and follow-up (such as advanced cancer and severe respiratory disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;hematoma volume;Modified Rankin Scale, mRS;EuroQol (EQ-5D);NIH Stroke Scale, NIHSS;Glasgow Coma Scale, GCS; | — |
Countries
China
Contacts
Public ContactXiao-pei SUN
Outcome results
None listed