primary liver cancer
Conditions
Interventions
A:preoperative radiotherapy+three weeks rest+radical resection
B:radical resection
Sponsors
Eastern Hepatobiliary Surgical Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20 to 70 years old male or female hepatocellular carcinoma patient; 2. karnofsky score 0-2; 3. liver function is Child-Pugh A or B; 4. single tumor; 5. with high-risk of microvascular invasion, no extrahepatic metastasis; 6. vascular invasion; no Portal vein tumor thrombus; 8. the liver volume of clinical target volume(CTV) in radiotherapy is less than the total liver volume 2/3; 9. Patients should sign the informed consent of this study.
Exclusion criteria
Exclusion criteria: 1. Operation resection scope beyond "Primary liver cancer diagnosis and treatment standard 2011"; 2. unradical resection of liver tumors; 3. Progress of tumor after radiotherapy can not be radical operated; 4. before enrollment received chemotherapy, radiotherapy, biological therapy, or participated in any other drug or therapy clinical trials by the instrument; 5. Liver, kidney and heart dysfunction; 6. the liver volume of clinical target volume(CTV) in radiotherapy is more than the total liver volume 2/3; 7. Researchers believe that those who should not participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival;radiographic parameters;Recurrent rates and Survival rates in 1,2,3,5 year; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alpha fetoprotein;Liver function; | — |
Contacts
Public ContactCheng Shuqun, Zheng Yaxin
Eastern Hepatobiliary Surgical Hospital
Outcome results
None listed