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Using Febuxostat for acute attacks of gout: a randomized clinical trial

Using Febuxostat for acute attacks of gout: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-14005486
Enrollment
Unknown
Registered
2014-10-13
Start date
2014-11-14
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gout

Interventions

Test group:Westen medical treatmentswith uricosuric
Control:Routine treatment of Westen medicine

Sponsors

The Affiliated Hospital of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Consistent with primary gout clinical manifestations; 2. Within 7 days of onset of an acute gout attack; 3. Aged 18 to 70 years old, male or female.

Exclusion criteria

Exclusion criteria: 1. secondary gout (caused by blood disease, kidney disease or tumor); 2. the presence of tophaceous gout; 3. severe liver and kidney dysfunction (the hepatic enzyme is 3 times higher than the normal value); 4. serum creatinine greater than the normal value; 5. have serious heart disease, such as ischemic heart disease, decompensated heart failure, unstable angina, ischemic peripheral vascular disease and myocardial infarction within 12 months; 6.use of steroids, colchicine, allopurinol, benzbromarone, immunosuppressive therapy in the past 6 months; 7. allergic to NSAIDS, colchicine, febuxostat orbe hypersensitive; 8. white blood cell count less than 4*10^9/L, or blood platelet count less than 100*10^9/L, or hemoglobin count less than 90g/L; 9.have serious infection; 10. have alcohal addiction?drug addiction or mental disorder; 11.malignant tumor or active tuberculosis; 12. the compliance is poor or have some other disese which can affect the research.

Design outcomes

Primary

MeasureTime frame
VAS;serum uric acid;recurrence rate;

Secondary

MeasureTime frame
C-reactive protein levels;interleukin beta 1;tumor necrosis factor;erythrocyte sedimentation rate (ESR);serum creatinine;

Countries

China

Contacts

Public ContactLi Changgui
lichanggui@medmail.com.cn+86 13969620056

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026