gout
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Consistent with primary gout clinical manifestations; 2. Within 7 days of onset of an acute gout attack; 3. Aged 18 to 70 years old, male or female.
Exclusion criteria
Exclusion criteria: 1. secondary gout (caused by blood disease, kidney disease or tumor); 2. the presence of tophaceous gout; 3. severe liver and kidney dysfunction (the hepatic enzyme is 3 times higher than the normal value); 4. serum creatinine greater than the normal value; 5. have serious heart disease, such as ischemic heart disease, decompensated heart failure, unstable angina, ischemic peripheral vascular disease and myocardial infarction within 12 months; 6.use of steroids, colchicine, allopurinol, benzbromarone, immunosuppressive therapy in the past 6 months; 7. allergic to NSAIDS, colchicine, febuxostat orbe hypersensitive; 8. white blood cell count less than 4*10^9/L, or blood platelet count less than 100*10^9/L, or hemoglobin count less than 90g/L; 9.have serious infection; 10. have alcohal addiction?drug addiction or mental disorder; 11.malignant tumor or active tuberculosis; 12. the compliance is poor or have some other disese which can affect the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS;serum uric acid;recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| C-reactive protein levels;interleukin beta 1;tumor necrosis factor;erythrocyte sedimentation rate (ESR);serum creatinine; | — |
Countries
China