Skip to content

White matter and obsessive-compulsive disorder: the mechanism and target of cognitive behavior therapy

White matter and obsessive-compulsive disorder: the mechanism and target of cognitive behavior therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOR-14005436
Enrollment
Unknown
Registered
2014-10-29
Start date
2015-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obsessive-compulsive disorder

Interventions

CBT therapy:Cognitive behavior therapy
Drug therapy:SSRI medication
normal control:No treatment

Sponsors

Beijing Anding Hospital affiliated Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: (1) met the DSM-IV-TR diagnostic criteria for OCD, using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I); (2) Y-BOCS score more than 11 and HAMD score less than 18; (3) age between 20 and 45 years;right handedness; (4) Medication naive or medication free for at least 4 weeks prior to enrollment.

Exclusion criteria

Exclusion criteria: 1. had history of neurological illness or other major physical diseases; 2. had history of Axis I psychiatric disorders other than obsessive-compulsive disorder; 3. had history of psycho-active substance use, alcohol dependence, and/or abuse; 4. had previous exposure to at least 12 sessions of CBTand being pregnant.

Design outcomes

Primary

MeasureTime frame
Yale-Brown Obsessive-Compulsive Scale;Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;

Countries

China

Contacts

Public ContactZhanJiang LI
lizhanjiang1221@sina.com+86 58303004

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 2, 2026