Cardiac Valve disease
Conditions
Interventions
Control and ILPCgroup:Step 1: Intralipid postconditioning
Control vs ILPC-0min vs ILPC-10min:Step 2: Intralipid postconditioning was applied at
Sponsors
West China Hospital, Sichuan University
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The ethics committee of our institution approved the study. Written informed consent was obtained from all patients before inclusion. Consecutive patients scheduled for aortic valve surgery or mitral valve surgery, older than 18yr, were eligible for enrollment.
Exclusion criteria
Exclusion criteria: Exclusion criteria were emergency surgery, combined coronary surgery, significant coronary stenosis(less than 70%), left ventricular (LV) ejection fraction less than 40%, renal insufficiency (serum creatinine level more than 150 umol/l),severe hepatic dysfunction, uncontrolled hypertension and hyperglycemia, current infections, any disorder associated with immunological dysfunction (e.g., malignancy, positive serologic test for the human immunodeficiency virus) in the last 6 months before presentation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cTNI;CK-MB;BNP;h-FABP; | — |
Secondary
| Measure | Time frame |
|---|---|
| major adverse events occurring during;length of stay in hospital;length of stay in intensive care unit;extubation time;the use of the positive inotropic drugs;LVEF;hepatic function;renal function; | — |
Countries
China
Contacts
Public ContactRonghua Zhou
Outcome results
None listed