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Multimodal analgesia for total knee arthroplasty operation during perioperative period

Multimodal analgesia for total knee arthroplasty operation during perioperative period

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOQ-15005898
Enrollment
Unknown
Registered
2015-01-05
Start date
2015-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

total knee arthroplasty operation

Interventions

Multimodal analgesia group:Continuous catheterization of femoral nerve block + local anesthesia (Lo Pacan) + oxycodone + celecoxib
Ordinary analgesia group:Intravenous analgesia pump block + local anesthesia (Lo Pacan) + Intravenous analgesia pump (tramadol 500-700mg standards: 8mg/kg
Toland ondansetron 5mg)
partial closure (0.25% ropivacaine 80ml), after the surgery sooner or later the two oral oxycodone 330mg+ celecoxib capsules 200mg.

Sponsors

Department of orthopedics, People's Hospital of Karamay City
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: From January 2015 to December 2016 in people's Hospital Department of orthopedics, unilateral joint replacement patients 80 cases as the observation object. Patient younger than 80 years old; No cognitive impairment, communication difficulties or mental and neurological diseases; No alcohol or drug dependence syndrome; no morphine or local anesthetic allergy history; for the non steroidal anti-inflammatory drug allergy history; No liver and kidney dysfunction and coagulation dysfunction; No history of peptic ulcer disease and hemorrhagic disease history; The patients were informed consent, and approval from the hospital ethics committee.

Exclusion criteria

Exclusion criteria: (1) and body mass index (body, mass index, BMI) is greater than 35; (2) with chronic pain, neurological and psychiatric dysfunction or 1 weeks still take a variety of analgesic drugs in patients before operation; (3) with severe coagulopathy, active gastric ulcer or are receiving anticoagulant treatment in patients with; (4) bilateral knee OA or undergoing knee artificial revision arthroplasty patients; (5) the femoral nerve block puncture local infection or known to local anesthesia in patients with drug allergy medication and operation process; (6) with rheumatoid arthritis or severe systemic arthritis patients; (7) can not be a correct understanding and cooperation for VAS pain score and can not master the correct method of using patient controlled analgesia pump for patients; (8) patients before and after operation in an unexpected situation, long time operation, excessive tension and postoperative severe infections are excluded.

Design outcomes

Primary

MeasureTime frame
VAS;

Countries

China

Contacts

Public ContactYue Yong
yueyong54321@qq.com+86 18999505353

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026