Obesity and metabolic related diseases
Conditions
Interventions
Laparoscopic gastric bypass group:Laparoscopic gastric bypass
Laparoscopic sleeve gastrectomy group:Laparoscopic sleeve gastrectomy
Sponsors
The First Affiliated Hospital of Jinan University
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. According to the standard of obesity Obesity Task Force established in 2001, BMI=28k / m2 with obesity-related metabolic diseases in patients, or BMI=35kg / m2 in patients with severe obesity were selected; 2. Aged 20 to 60 years; 3. self-capacity, non-drug dependence, psychological illness; 4. not prompted stomach ulcers, erosions, tumors, polyps, atrophic gastritis and other stomach diseases in the preoperative endoscopy; 5. no history of stomach and abdominal surgery; 6. Case Source: First Affiliated Hospital of Jinan University, by the same team of doctors performed the surgical procedure.
Exclusion criteria
Exclusion criteria: All individuals that do not comply with the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| routine blood;serum biochemical;serum glycosylated hemoglobin;fasting blood glucose;C peptide;HP antibody;depth of gastric pits;thickness of gastric fundus gland;thickness of gastric submucosal layer;thickness of gastric submucosal layer;thickness of gastric mucosa;the number of gastric mucous cells;the number of primary cells;the number of parietal cells;diameter and number of fat cells in adipose tissue;Ghrelin;Petide YY;Glucagon-like peptide 2 (GLP2);Glucagon-like peptide 1 (GLP1);Glucagon (GC);Gastric inhibitory peptide (GIP);INSULIN;Adiponectin;Leptin;TNF-a;NLR pyrin domain containing 3;Interleukin-1ß (IL-1ß);Interleukin-6 (IL-6);Interleukin-18 (IL-18);C-reactive protein (CRP);Lipopolysaccharide;toll-like receptor 4 (TLR4);The depth of the pits between small intestine villi; | — |
Countries
China
Contacts
Public ContactJingge Yang
The First Affiliated Hospital of Jinan University
Outcome results
None listed