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The impact of Treg/Th17 cell with Daily or Intermittent corticosteroid in Preschool Children with Recurrent Wheezing

The impact of Treg/Th17 cell with Daily or Intermittent corticosteroid in Preschool Children with Recurrent Wheezing

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IOD-17011130
Enrollment
Unknown
Registered
2017-04-12
Start date
2017-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Interventions

Three groups:Different doses of Application of glucocorticoid inhalation

Sponsors

Pediatrics Department, Southwest Hospital, The Third Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Less than 5 years old; 2. Although initial diagnosis and always diagnosed with asthma but not yet according to the specification of asthma treatment; 3. Did not receive treatment such as inhaled corticosteroids, leukotriene receptor antagonists in two weeks.

Exclusion criteria

Exclusion criteria: 1. nearly 2 weeks of oral or intravenous use of glucocorticoids or immune modulators; 2. associated with other autoimmune diseases such as tuberculosis, systemic lupus erythematosus, juvenile idiopathic arthritis; 3. the incidence of 4 weeks had been suffering from infectious diseases, including upper respiratory tract infection, pneumonia; 4. the function of heart and lung failure.

Design outcomes

Primary

MeasureTime frame
Treg cells;Th17 cells;ROR-?t;FOXP3+;

Secondary

MeasureTime frame
IL-10;IL-17;IL-6;

Countries

China

Contacts

Public ContactWei liao

Pediatrics Department, Southwest Hospital, The Third Military Medical University

liaowei01@163.com+86 13896043391

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026