Brain radiation necrosis
Conditions
Interventions
1:5mg/kg Bevacizumab
2:1 mg/kg Bevacizumab
Sponsors
Tianjin Medical University Cancer Institute and Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients with brain primary or metastatic tumors; 2. SRS history of intracranial lesions; 3. Pathological puncture or imaging diagnosis of brain radiation necrosis.
Exclusion criteria
Exclusion criteria: 1. Tumor recurrence, or not control lesion; 2. False progress after the treatment; 3. Activity period of hemorrhagic disease; 4. The digestive tract perforation, need medical treatment of wounds cracking; severe bleeding, nephrotic syndrome or hypertensive crisis and other contraindications to bevacizumab.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Edema index; | — |
Countries
China
Contacts
Public ContactHongqing Zhuang
Tianjin Medical University Cancer Institute and Hospital
Outcome results
None listed