skull defects
Conditions
Interventions
1:Titanium mesh
Sponsors
The First People's Hospital of Wujiang District
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Unilateral frontotemporal skull defects; 2. Skull defect diameter > 3 cm; 3. Skull repair 3 months after decompressive craniectomy; 4. Consciousness, Glasgow Coma Scale scores>13; 5. Stable heart, lung, liver and kidney indicators; 6. Aged from 20 to 70 years old.
Exclusion criteria
Exclusion criteria: 1. Skin infection at the surgical area; 2. No obvious edema, no obvious shift in the midline structure, or no obvious ventricular dilatation revealed by skull CT scan; 3. Intracranial hypertension after decompressive craniectomy; 4. Thin scalp at the defect site; 5. Asymmetrical bilateral skulls before first craniotomy; 6. Severe heart, liver, and kidney dysfunction; 7. Poor general conditions; 8. Severe neurological deficits; 9. Possibly sensitive to titanium mesh materials; 10. Participation in other material clinical trials within 3 months; 11. Pregnancy, suspected pregnancy and breastfeeding women.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Glasgow Outcome Scale;Karnofsky Performance Scale;National Institute of Health Stroke Scale;Skull CT scans;Surgical indicators; | — |
Primary
| Measure | Time frame |
|---|---|
| incidence of complications; | — |
Countries
China
Contacts
Public ContactWei Qian
The First People's Hospital of Wujiang District
Outcome results
None listed